Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (509 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.996
pgK
Phosphoglycerate kinase; Similar to Bacillus megaterium phosphoglycerate kinase Pgk SWALL:PGK_BACME (SWALL:P24269) (394 aa) fasta scores: E(): 2.4e-80, 57.07 38d in 396 aa, and to Clostridium acetobutylicum phosphoglycerate kinase Pgk or cac0710 SWALL:PGK_CLOAB (SWALL:O52632) (397 aa) fasta scores: E(): 5.4e-110, 77.44 38d in 399 aa.
  
 
 0.992
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.956
CBO1096
Putative metallo-beta-lactamase superfamily protein.
   
 0.949
fba
Similar to Entamoeba histolytica putative fructose-1,6-bisphosphate aldolase Ald SWALL:Q8MTW2 (EMBL:AY057996) (326 aa) fasta scores: E(): 5.8e-51, 49.2 id in 315 aa, and to Clostridium tetani fructose-bisphosphate aldolase ctc00341 SWALL:Q898U8 (EMBL:AE015937) (320 aa) fasta scores: E(): 3.3e-80,76.75 38d in 314 aa.
   
 
 0.940
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.933
CBO2235
Putative glycerate kinase; Belongs to the glycerate kinase type-1 family.
     
 0.914
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.912
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.908
serA
Putative D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.906
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.