Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kdgTSimilar to Erwinia chrysanthemi 2-keto-3-deoxygluconate permease KdgT SWALL:KDGT_ERWCH (SWALL:P15701) (339 aa) fasta scores: E(): 2.4e-33, 38.43 id in 307 aa, and to Erwinia carotovora 2-keto-3-deoxygluconate permease KdgT SWALL:KDGT_ERWCA (SWALL:Q9XB52) (318 aa) fasta scores: E(): 3.1e-36, 41.29 id in 310 aa. (324 aa)    
Predicted Functional Partners:
kdgA
Similar to Bacillus subtilis khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase KdgA or bsu22100 SWALL:ALKH_BACSU (SWALL:P50846) (196 aa) fasta scores: E(): 4.1e-17, 35.6 38d in 191 aa, and to Streptococcus agalactiae 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase eda-2 or sag1907 SWALL:Q8DXE4 (EMBL:AE014277) (212 aa) fasta scores: E(): 1.6e-39, 54.76 38d in 210 aa.
  
  
 0.787
CBO2209
Conserved hypothetical protein.
 
   
 0.659
CBO0248
Two-component sensor kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 sensor protein DcuS or b4125 or z5727 or ecs5107 SWALL:DCUS_ECOLI (SWALL:P39272) (543 aa) fasta scores: E(): 1.4e-44, 31.09 38d in 537 aa, and to Clostridium tetani sensor kinase DpiB or ctc01524 SWALL:Q894L7 (EMBL:AE015941) (538 aa) fasta scores: E(): 4.2e-67,41.17 38d in 544 aa.
 
     0.567
pdxA
Putative 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family.
 
     0.539
CBO0249
Two-component response regulator; Similar to Bacillus subtilis probable c4-dicarboxylate response regulator dctr dctr or bsu04460 SWALL:DCTR_BACSU (SWALL:P96602) (226 aa) fasta scores: E(): 1e-26, 40 38d in 220 aa.
     
 0.505
CBO0246
Similar to Corynebacterium melassecola malic enzyme MalE SWALL:Q9KIF8 (EMBL:AF234535) (392 aa) fasta scores: E(): 3.3e-63, 52.91 38d in 378 aa, and to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 2.7e-57, 48.88 id in 403 aa; Also similar to CBO0210 (66.6 38d).
       0.476
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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