STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO0255Putative reductase; Similar to Thermotoga maritima dihydrofolate reductase FolA or DyrA or tm1641 SWALL:DYR_THEMA (SWALL:Q60034) (169 aa) fasta scores: E(): 0.00064, 24.56 id in 171 aa, and to Bacillus cereus pyrimidine reductase bc0650 SWALL:Q813Y8 (EMBL:AE017000) (173 aa) fasta scores: E(): 1.8e-16, 37.19 38d in 164 aa. (174 aa)    
Predicted Functional Partners:
CBO0768
Putative phage-related deoxyuridylate hydroxymethyltransferase.
  
  
 0.730
CBO0254
Putative acetyltransferase; Similar to Listeria innocua hypothetical protein Lin2361 SWALL:Q929B6 (EMBL:AL596172) (291 aa) fasta scores: E(): 3.5e-39, 37.75 38d in 294 aa, and to Bacillus halodurans hypothetical protein Bh3929 bh3929 SWALL:Q9K606 (EMBL:AP001520) (286 aa) fasta scores: E(): 1.7e-23,30.47 38d in 292 aa.
  
    0.697
CBO0256
Putative exonuclease; Similar to Clostridium acetobutylicum DNA polymerase III epsilon subunit cac0738 SWALL:Q97L28 (EMBL:AE007589) (306 aa) fasta scores: E(): 7.7e-76,68.75 38d in 304 aa.
 
     0.639
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
 
 0.550
CBO0253
Cytidine deaminase; Similar to Bacillus caldolyticus cytidine deaminase Cdd SWALL:Q9R2S1 (EMBL:AJ237979) (132 aa) fasta scores: E(): 1.2e-05, 30.4 38d in 125 aa, and to Aspergillus terreus blasticidin-S deaminase Bsd SWALL:BSD_ASPTE (SWALL:P78986) (130 aa) fasta scores: E(): 3.9e-05, 31.49 id in 127 aa.
  
  
 0.471
CBO0183
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family.
  
 
 0.453
birA
BirA bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.453
tepA
Translocation-enhancing protein TepA.
    
 
 0.401
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
    
 
 0.401
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.