STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdA1Similar to Paracoccus pantotrophus cytochrome C biogenesis protein CcdA SWALL:Q9EYZ1 (EMBL:AF308446) (247 aa) fasta scores: E(): 3.3e-25, 37.44 38d in 211 aa, and to Bacillus subtilis cytochrome C-type biogenesis protein CcdA or bsu17930 SWALL:CCDA_BACSU (SWALL:P45706) (235 aa) fasta scores: E(): 1.8e-21, 32.03 38d in 231 aa. (227 aa)    
Predicted Functional Partners:
resA
Similar to Bacillus subtilis thiol-disulfide oxidoreductase ResA or bsu23150 SWALL:RESA_BACSU (SWALL:P35160) (179 aa) fasta scores: E(): 2.6e-11, 29.03 id in 186 aa.
  
 0.995
CBO0261
Putative exported protein; Similar to Clostridium perfringens hypothetical protein Cpe1837 SWALL:Q8XJC3 (EMBL:AP003192) (146 aa) fasta scores: E(): 1.4, 29.66 38d in 118 aa.
       0.765
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.699
CBO1820
Thioredoxin.
  
  
 0.661
CBO0265
Two-component sensor kinase; Similar to Clostridium perfringens two-component sensor histidine kinase cpe2331 SWALL:Q8XHZ3 (EMBL:AP003193) (467 aa) fasta scores: E(): 1.2e-57,38.36 38d in 464 aa.
       0.655
trxB2
Thioredoxin reductase.
 
  
 0.654
CBO0264
Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 7.1e-27, 41.66 38d in 228 aa, and to Thermoanaerobacter tengcongensis response regulators consisting of a chey-like receiver domain and a hth DNA-binding domain ompr6 or tte2474 SWALL:Q8R7E1 (EMBL:AE013188) (231 aa) fasta scores: E(): 3.6e-39,51.32 38d in 226 aa.
       0.646
trxA
Thioredoxin; Belongs to the thioredoxin family.
  
  
 0.616
trxC
Thioredoxin; Belongs to the thioredoxin family.
  
  
 0.616
CBO0141
Putative zinc transporter; Similar to Escherichia coli, Escherichia coli O6,and Escherichia coli O157:H7 zinc transporter ZupTt or b3040 or c3789 or z4397 or ecs3928 SWALL:ZUPT_ECOLI (SWALL:P24198) (257 aa) fasta scores: E(): 3.9e-08, 27.53 id in 247 aa, and to Clostridium tetani zinc uptake transporter ctc00304 SWALL:Q898Y3 (EMBL:AE015936) (236 aa) fasta scores: E(): 8.5e-49, 53.81 38d in 236 aa.
   
    0.585
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.