Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0264Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 7.1e-27, 41.66 38d in 228 aa, and to Thermoanaerobacter tengcongensis response regulators consisting of a chey-like receiver domain and a hth DNA-binding domain ompr6 or tte2474 SWALL:Q8R7E1 (EMBL:AE013188) (231 aa) fasta scores: E(): 3.6e-39,51.32 38d in 226 aa. (225 aa)    
Predicted Functional Partners:
CBO0265
Two-component sensor kinase; Similar to Clostridium perfringens two-component sensor histidine kinase cpe2331 SWALL:Q8XHZ3 (EMBL:AP003193) (467 aa) fasta scores: E(): 1.2e-57,38.36 38d in 464 aa.
 
 
 0.960
CBO0336
Similar to Clostridium acetobutylicum sensory transduction histidine kinase cac0903 SWALL:Q97KL4 (EMBL:AE007605) (683 aa) fasta scores: E(): 3e-47, 32.62 id in 610 aa.
 
 
 0.881
CBO0340
Two-component sensor kinase; Similar to Clostridium acetobutylicum sensory transduction histidine kinase cac0903 SWALL:Q97KL4 (EMBL:AE007605) (683 aa) fasta scores: E(): 1.1e-45,34.81 38d in 586 aa.
 
 
 0.849
CBO1042
Two-component sensor kinase.
 
 
 0.830
CBO1036
Two-component sensor kinase.
 
 
 0.823
CBO0608
Two-component sensor kinase.
 
 
 0.806
CBO3349
Two-component sensor kinase.
 
   0.801
CBO1967
Two-component sensor kinase.
 
 
 0.797
CBO0611
Two-component sensor kinase.
 
 
 0.792
CBO0780
Two component sensor kinase.
  
   0.792
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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