Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0284Rrf2-family transcriptional regulator; Similar to Bacillus anthracis rrf2 family protein ba4743 SWALL:Q81L85 (EMBL:AE017038) (143 aa) fasta scores: E(): 2e-33, 65.03 38d in 143 aa. (143 aa)    
Predicted Functional Partners:
CBO0286
Similar to Chromobacterium violaceum hypothetical protein cv0714 SWALL:AAQ58390 (EMBL:AE016912) (212 aa) fasta scores: E(): 5.1e-27, 45.07 38d in 213 aa.
 
  
 0.915
iscS
Cysteine desulfurase.
  
  
 0.631
iscS-2
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
  
 0.631
nifU
Conserved hypothetical protein; Similar to the N-terminal region of Azotobacter vinelandii nitrogen fixation protein NifU SWALL:NIFU_AZOVI (SWALL:P05340) (312 aa) fasta scores: E(): 1e-21, 52.94 id in 119 aa. Full length CDS is similar to Clostridium perfringens probable nitrogen fixation protein NifU or CPE1784 SWALL:Q8XJH2 (EMBL:AP003191) (142 aa) fasta scores: E(): 1.3e-45, 82.27 38d in 141 aa.
  
  
 0.560
CBO0285
Putative isomerase; Similar to Pseudomonas putida 2-hydroxychromene-2-carboxylate isomerase NahD SWALL:NAHD_PSEPU (SWALL:Q51948) (203 aa) fasta scores: E(): 0.00039, 24 38d in 200 aa, and to Burkholderia sp. DBT1 DbtD SWALL:Q93NA9 (EMBL:AF380367) (207 aa) fasta scores: E(): 1.9e-07, 25.37 38d in 201 aa.
  
    0.555
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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