STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cssSTwo-component sensor kinase; Similar to Bacillus subtilis sensor protein CssS or bsu33020 SWALL:CSSS_BACSU (SWALL:O32193) (451 aa) fasta scores: E(): 9e-33, 30.17 38d in 464 aa. (461 aa)    
Predicted Functional Partners:
cssR
Two-component response regulator; Similar to Bacillus subtilis transcriptional regulatory protein CssR or bsu33010 SWALL:CSSR_BACSU (SWALL:O32192) (225 aa) fasta scores: E(): 1.1e-40, 50.89 id in 224 aa.
 
  0.996
CBO0264
Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 7.1e-27, 41.66 38d in 228 aa, and to Thermoanaerobacter tengcongensis response regulators consisting of a chey-like receiver domain and a hth DNA-binding domain ompr6 or tte2474 SWALL:Q8R7E1 (EMBL:AE013188) (231 aa) fasta scores: E(): 3.6e-39,51.32 38d in 226 aa.
 
   0.780
CBO1926
Two-component response regulator.
 
   0.779
CBO1041
Two-component response regulator.
 
   0.773
CBO0970
Two-component response regulator.
 
   0.769
CBO2285
Two-component response regulator.
 
   0.762
CBO1968
Two-component response regulator.
 
   0.759
CBO3349A
Two-component response regulator.
 
   0.759
CBO2527
Two-component response regulator.
 
   0.753
CBO1613
Two-component response regulator.
 
   0.752
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.