Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adhESimilar to Clostridium acetobutylicum aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Aad or cap0162 SWALL:ADHE_CLOAB (SWALL:P33744) (862 aa) fasta scores: E(): 2.6e-212,65.04 38d in 861 aa, and to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Ana or b1241 or z20 [...] (862 aa)    
Predicted Functional Partners:
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
  
 0.972
nifJ2
Pyruvate-flavodoxin oxidoreductase; Also similar to CBO1192 (65.74 38d).
  
 0.971
ctfA
Butyrate-acetoacetate CoA-transferase subunit A.
  
 
 0.969
ctfB
Butyrate-acetoacetate CoA-transferase subunit B.
  
 0.966
thl
acetyl-CoA acetyltransferase (thiolase); Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.966
pflA
Formate acetyltransferase.
 
 
 0.965
aldH
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.963
bcd
butyryl-CoA dehydrogenase.
  
 0.957
bdh
NADH-dependent butanol dehydrogenase.
 
 
0.952
ptA
Phosphate acetyltransferase.
  
 
 0.951
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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