Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO0399Similar to Bacillus subtilis methyl-accepting chemotaxis protein TlpB or bsu31230 SWALL:TLPB_BACSU (SWALL:P39217) (662 aa) fasta scores: E(): 2.6e-40, 31.81 id in 682 aa. (684 aa)    
Predicted Functional Partners:
cheB
Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.982
cheR
Chemotaxis protein methyltransferase.
 
 0.981
cheN
Chemotaxis protein CheA.
 
 0.978
cheD
Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.977
CBO2745
Similar to Clostridium tetani putative chemotaxis protein CTC01728 SWALL:Q893T1 (EMBL:AE015942) (134 aa) fasta scores: E(): 1.6e-30, 67.93 38d in 131 aa. Similar to an internal region of Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri chemotaxis protein CheW or b1887 or c2302 or z2941 or ecs2597 or sf1936 or s2027 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 1.5e-08, 31.34 38d in 134 aa.
 
 0.973
cheW
Chemotaxis protein CheW.
 
 0.973
cheV
Chemotaxis protein.
 
 0.959
cheY
Chemotaxis protein cheY homologue.
 
 
  0.866
CBO0998
Two-component response regulator.
 
  0.851
cheC
Chemotaxis protein CheC.
 
 
 0.749
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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