Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0410Conserved hypothetical protein; Similar to Clostridium acetobutylicum cobyric acid synthase CobQ cac0961 SWALL:Q97KF8 (EMBL:AE007611) (243 aa) fasta scores: E(): 8.8e-72, 77.08 38d in 240 aa. (242 aa)    
Predicted Functional Partners:
CBO0411
Mur ligase family protein; Similar to Clostridium acetobutylicum udp-N-acetylmuramyl tripeptide synthetase cac0962 SWALL:Q97KF7 (EMBL:AE007611) (435 aa) fasta scores: E(): 2.2e-112, 64.76 38d in 437 aa.
 0.999
murG
UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
     
 0.906
cphA
Similar to Anabaena variabilis cyanophycin synthetase CphA SWALL:CPHA_ANAVA (SWALL:O86109) (901 aa) fasta scores: E(): 5.5e-116, 39.86 38d in 868 aa, and to Clostridium tetani cyanophycin synthetase ctc00282 SWALL:Q899A3 (EMBL:AE015936) (874 aa) fasta scores: E(): 3e-189, 57.98 38d in 864 aa.
  
 
 0.816
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 
 0.780
CBO3158
Conserved hypothetical protein.
  
 
 0.780
manA
Similar to Streptococcus mutans mannose-6-phosphate isomerase Pmi or ManA or smu.1839 SWALL:MANA_STRMU (SWALL:Q59935) (316 aa) fasta scores: E(): 1.1e-29, 35.25 id in 312 aa.
       0.480
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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