Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
manASimilar to Streptococcus mutans mannose-6-phosphate isomerase Pmi or ManA or smu.1839 SWALL:MANA_STRMU (SWALL:Q59935) (316 aa) fasta scores: E(): 1.1e-29, 35.25 id in 312 aa. (326 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 
 0.960
ptsM
Putative transposase (partial); Pfam match to entry PF00665 rve, Integrase core domain, score 114.4, E-value 2.2e-31.
 
  
 0.933
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.932
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.930
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.916
fbp
Fructose-1,6-bisphosphatase.
     
 0.908
srlD
Sorbitol-6-phosphate 2-dehydrogenase.
   
 
 0.908
glpX
Putative fructose-1,6-bisphosphatase class II GlpX.
     
  0.900
CBO1991
PTS system, IIbc component.
  
  
 0.761
glcK
Putative glucokinase.
 
  
 0.738
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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