Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0418Putative aconitase; Similar to Clostridium acetobutylicum aconitase a cac0971 SWALL:Q97KE8 (EMBL:AE007613) (642 aa) fasta scores: E(): 4e-183, 76.01 38d in 642 aa. (641 aa)    
Predicted Functional Partners:
CBO0419
Similar to Coccidioides immitis isocitrate dehydrogenase IcdH SWALL:Q8X1D0 (EMBL:AF439265) (347 aa) fasta scores: E(): 2e-58, 51.35 38d in 333 aa.
 
 0.973
atpA-2
ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.897
CBO0417
Putative 2-isopropylmalate synthase; Similar to Streptomyces hygroscopicus 2-phosphinomethylmalic acid synthase PmmS SWALL:Q9LCB4 (EMBL:AB029822) (440 aa) fasta scores: E(): 3.5e-55,38.53 38d in 436 aa, and to Salmonella typhimurium 2-isopropylmalate synthase LeuA or stm0113 SWALL:LEU1_SALTY (SWALL:P15875) (522 aa) fasta scores: E(): 7.1e-10, 25.91 38d in 355 aa.
 
 
 0.858
crt
3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.849
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.838
CBO2602
Putative malate/lactate dehydrogenase; Weakly similar to many L-lactate dehydrogenases. Possible alternative translational start sites downstream of the current one.
  
 0.838
rpmF
50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.819
acoB
Acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit.
   
 0.801
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.792
hymB
Putative electron-transferring subunit of iron-only hydrogenase.
  
 
 0.782
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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