Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0428Similar to Clostridium tetani hypothetical protein ctc01031 SWALL:Q896H3 (EMBL:AE015939) (222 aa) fasta scores: E(): 1.8e-19, 37.44 38d in 211 aa. (216 aa)    
Predicted Functional Partners:
CBO0429
Similar to Clostridium tetani conserved protein ctc01032 SWALL:Q896H2 (EMBL:AE015939) (235 aa) fasta scores: E(): 1.1e-41, 50.67 38d in 223 aa.
       0.828
htpG
Chaperone protein; Molecular chaperone. Has ATPase activity.
  
 0.631
dnaK
Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.622
CBO1003
Putative ATPase.
  
 0.578
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.577
alaS
Putative alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.571
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.562
CBO2505
Putative protein phosphatase.
    
  0.539
ppiB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
 0.528
CBO0177
Putative RNA binding protein; Similar to Clostridium tetani transcription accessory protein ctc00330 SWALL:Q898V8 (EMBL:AE015937) (718 aa) fasta scores: E(): 7.4e-199, 77.99 38d in 718 aa.
   
 0.522
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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