Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO0447Putative membrane protein; Similar to Thermoanaerobacter tengcongensis sam-dependent methyltransferases smta5 or tte2398 SWALL:Q8R7K7 (EMBL:AE013182) (222 aa) fasta scores: E(): 0.0023, 25.22 38d in 218 aa. (242 aa)    
Predicted Functional Partners:
CBO1759
Putative methyltransferase.
  
     0.531
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.520
CBO0445
Binding-protein-dependent transport system,membrane component; Similar to Listeria innocua hypothetical protein Lin1851 lin1851 SWALL:Q92AR8 (EMBL:AL596170) (213 aa) fasta scores: E(): 2.2e-40, 51.65 38d in 211 aa.
   
   0.497
CBO0446
Binding-protein-dependent transport system,permease component; Similar to Escherichia coli, and Escherichia coli O6 cystine-binding periplasmic protein precursor FliY or b1920 or c2335 SWALL:FLIY_ECOLI (SWALL:P39174) (266 aa) fasta scores: E(): 5.9e-25, 33.84 38d in 260 aa; Belongs to the bacterial solute-binding protein 3 family.
       0.479
birA
BirA bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.410
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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