Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0468Putative AraC-family transcriptional regulator; Similar to Thermoplasma volcanium hypothetical protein tv0916 tv0916 or tvg0944468 SWALL:Q97A94 (EMBL:AP000994) (245 aa) fasta scores: E(): 1.5e-05,27.95 38d in 186 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ubiquinone/menaquinone biosynthesis methyltransferase ubie ubie or b3833 or z5355 or ecs4763 or sf3911 or s3843 SWALL:UBIE_ECOLI (SWALL:P27851) (251 aa) fasta scores: E(): 1.6e-05, 30 38d in 170 aa. (196 aa)    
Predicted Functional Partners:
CBO0467
Putative membrane protein; Similar to Thermotoga maritima hypothetical protein Tm0858 SWALL:Q9WZW2 (EMBL:AE001752) (168 aa) fasta scores: E(): 9.9e-15, 35.4 38d in 161 aa.
 
     0.897
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.520
CBO0466
Putative membrane protein; Similar to Clostridium perfringens hypothetical protein Cpe0713 SWALL:Q8XMH6 (EMBL:AP003187) (154 aa) fasta scores: E(): 3, 21.93 38d in 155 aa.
       0.470
birA
BirA bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.410
CBO1629
Conserved hypothetical protein.
  
     0.402
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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