Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SagAPutative cytolysin; Similar to Streptococcus iniae bacteriocin-like prepropeptide SagA SWALL:Q8GP18 (EMBL:AF465842) (54 aa) fasta scores: E(): 6.2e-06, 50 38d in 52 aa, and to Streptococcus pyogenes, Streptococcus pyogenes streptolysin S associated protein SagA or spy0738 or spym18_0799 or spym3_0480 or sps1374 SWALL:O69194 (EMBL:AF067723) (53 aa) fasta scores: E(): 0.00037, 42 38d in 50 aa. (60 aa)    
Predicted Functional Partners:
SagB
Putative cytolysin-associated protein; Similar to Streptococcus equisimilis SagB SWALL:Q93SL4 (EMBL:AY033399) (316 aa) fasta scores: E(): 5.8e-45, 44.17 38d in 292 aa.
       0.465
sagC
Putative cytolysin-associated protein; Similar to Streptococcus iniae SagC SWALL:Q8GP16 (EMBL:AF465842) (354 aa) fasta scores: E(): 2.6e-38,36.33 38d in 355 aa.
       0.465
sagD
Putative cytolysin-associated protein; Similar to Streptococcus iniae SagD sagD SWALL:Q8GP15 (EMBL:AF465842) (453 aa) fasta scores: E(): 9.8e-91, 51.54 38d in 454 aa.
       0.443
sagE
Putative cytolysin-associated protein; Similar to Streptococcus iniae SagE SWALL:Q8GP14 (EMBL:AF465842) (220 aa) fasta scores: E(): 1.9e-18,32.05 38d in 209 aa.
       0.443
sagF
Putative cytolysin-associated protein; Similar to Streptococcus iniae SagF SWALL:Q8GP13 (EMBL:AF465842) (229 aa) fasta scores: E(): 0.15, 26 38d in 150 aa.
       0.443
CBO0485
Similar to Clostridium tetani conserved protein ctc00792 SWALL:Q897E8 (EMBL:AE015938) (343 aa) fasta scores: E(): 1e-48, 40.81 38d in 343 aa.
       0.403
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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