STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0504Putative peptidoglycan hydrolase. (718 aa)    
Predicted Functional Partners:
CBO1446
Putative secreted protease; Extracellular zinc metalloprotease.
  
 
 0.724
CBO2999
Penicillin-binding protein.
  
  
 0.719
CBO1374
Putative gamma-D-glutamyl-L-diamino acid endopeptidase.
  
  
 0.697
rumA
Putative RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
 
   
 0.692
CBO2011
Putative exported protein.
     
 0.690
radA
DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.690
rumA-2
Putative RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
 
   
 0.683
CBO3179
Conserved hypothetical protein; Contains Pfam matches (PF03734, PF01471) which suggests that this is an enzyme which interacts with peptidoglycan.
  
  
 0.651
ftsX
Cell division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 
 0.644
CBO0062
Putative exported peptidoglycan lytic protein; Similar to Listeria monocytogenes p45 precursor spl or lmo2505 SWALL:Q9RE04 (EMBL:AJ250194) (401 aa) fasta scores: E(): 2.4e-15, 31.18 38d in 388 aa, and to Clostridium acetobutylicum cell wall-associated hydrolase cac0308 SWALL:Q97M90 (EMBL:AE007545) (392 aa) fasta scores: E(): 2.2e-27, 36.84 38d in 380 aa.
  
  
 0.617
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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