STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO0504Putative peptidoglycan hydrolase. (718 aa)    
Predicted Functional Partners:
CBO1374
Putative gamma-D-glutamyl-L-diamino acid endopeptidase.
  
  
 0.725
CBO2999
Penicillin-binding protein.
  
  
 0.697
CBO1722
Terminase large subunit.
     
 0.672
CBO2355
Terminase large subunit.
     
 0.672
CBO1424
Putative N-acetylmuramoyl-L-alanine amidase; Also similar to prophage encoded CBO1751, CBO1653,CBO3016 and CBO2325.
  
  
 0.652
CBO3179
Conserved hypothetical protein; Contains Pfam matches (PF03734, PF01471) which suggests that this is an enzyme which interacts with peptidoglycan.
     
 0.649
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
  
  
 0.548
CBO0062
Putative exported peptidoglycan lytic protein; Similar to Listeria monocytogenes p45 precursor spl or lmo2505 SWALL:Q9RE04 (EMBL:AJ250194) (401 aa) fasta scores: E(): 2.4e-15, 31.18 38d in 388 aa, and to Clostridium acetobutylicum cell wall-associated hydrolase cac0308 SWALL:Q97M90 (EMBL:AE007545) (392 aa) fasta scores: E(): 2.2e-27, 36.84 38d in 380 aa.
 
  
0.546
CBO2504
Putative serine/threonine-protein kinase.
 
  
 0.510
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
   
 0.480
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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