Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO0573Probable tRNA-binding protein; Similar to the C-terminal regions of various methionyl-tRNA synthetase such as Escherichia coli methionyl-tRNA synthetase MetG, and similar over the entire length of certain proteins such as Pyrococcus abyssi fragment of methionyl-tRNA synthetase pyrab04130 or pab0278 SWALL:Q9V1L4 (EMBL:AJ248284) (109 aa) fasta scores: E(): 6e-11, 43 38d in 100 aa. (116 aa)    
Predicted Functional Partners:
pheS
phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
  
 
 0.894
purL
Formylglycinamidine ribonucleotide synthetase.
  
  
 0.622
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.528
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.462
lepB
Signal peptidase; Belongs to the peptidase S26 family.
       0.459
CBO2819
Putative iron-sulfur oxidoreductase.
  
  
 0.422
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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