Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0617Putative arsenical resistance operon repressor; The C-terminal region of this CDS is similar to arsenical resistance genes such as Staphylococcus aureus arsenical resistance operon repressor ArsR SWALL:ARSR_STAAU (SWALL:P30338) (104 aa) fasta scores: E(): 0.0047, 38.27 38d in 81 aa, and its N-terminal region is similar to several including Plasmodium yoelii yoelii putative bir1 protein py02660 SWALL:EAA22137 (EMBL:AABL01000733) (346 aa) fasta scores: E(): 1.2,23.21 38d in 224 aa, and Bacillus subtilis RNA polymerase sigma-G factor SigG or SpoIIIG or bsu15330 SWALL:RPSG_BACSU (SWALL:P19 [...] (343 aa)    
Predicted Functional Partners:
arsC
Arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.833
arsB
Putative arsenical pump membrane protein.
 
  
 0.617
CBO0618
ABC transporter, ATP-binding/permease protein.
 
    0.561
CBO0183
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family.
  
  
 0.507
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.