| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBO0037 | pnpA | CBO0037 | CBO2413 | Putative NUDIX-family hydrolase; Similar to Clostridium tetani predicted NADH pyrophosphatase ctc00069 SWALL:Q899U7 (EMBL:AE015936) (175 aa) fasta scores: E(): 5.5e-45, 70 38d in 160 aa, and to Clostridium acetobutylicum N-terminal Zn-ribbon domain and C-terminal MutT domain, yjad ortholog cac0145 SWALL:Q97MP7 (EMBL:AE007526) (174 aa) fasta scores: E(): 4.7e-34,54.37 38d in 160 aa. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.736 |
| CBO0037 | rhlE | CBO0037 | CBO0643 | Putative NUDIX-family hydrolase; Similar to Clostridium tetani predicted NADH pyrophosphatase ctc00069 SWALL:Q899U7 (EMBL:AE015936) (175 aa) fasta scores: E(): 5.5e-45, 70 38d in 160 aa, and to Clostridium acetobutylicum N-terminal Zn-ribbon domain and C-terminal MutT domain, yjad ortholog cac0145 SWALL:Q97MP7 (EMBL:AE007526) (174 aa) fasta scores: E(): 4.7e-34,54.37 38d in 160 aa. | Putative ATP-dependent RNA helicase rhle; Belongs to the DEAD box helicase family. | 0.707 |
| CBO0037 | rho | CBO0037 | CBO0134 | Putative NUDIX-family hydrolase; Similar to Clostridium tetani predicted NADH pyrophosphatase ctc00069 SWALL:Q899U7 (EMBL:AE015936) (175 aa) fasta scores: E(): 5.5e-45, 70 38d in 160 aa, and to Clostridium acetobutylicum N-terminal Zn-ribbon domain and C-terminal MutT domain, yjad ortholog cac0145 SWALL:Q97MP7 (EMBL:AE007526) (174 aa) fasta scores: E(): 4.7e-34,54.37 38d in 160 aa. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.510 |
| infA | rbfA | CBO3457 | CBO2417A | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.791 |
| infA | rhlE | CBO3457 | CBO0643 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Putative ATP-dependent RNA helicase rhle; Belongs to the DEAD box helicase family. | 0.696 |
| infA | rho | CBO3457 | CBO0134 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.570 |
| infA | rplC | CBO3457 | CBO3480 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.989 |
| infA | rplD | CBO3457 | CBO3479 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.997 |
| infA | rplJ | CBO3457 | CBO3490 | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.955 |
| nnrE | pnpA | CBO3399 | CBO2413 | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.478 |
| nnrE | rbfA | CBO3399 | CBO2417A | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.410 |
| nnrE | rhlE | CBO3399 | CBO0643 | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Putative ATP-dependent RNA helicase rhle; Belongs to the DEAD box helicase family. | 0.670 |
| pnpA | CBO0037 | CBO2413 | CBO0037 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Putative NUDIX-family hydrolase; Similar to Clostridium tetani predicted NADH pyrophosphatase ctc00069 SWALL:Q899U7 (EMBL:AE015936) (175 aa) fasta scores: E(): 5.5e-45, 70 38d in 160 aa, and to Clostridium acetobutylicum N-terminal Zn-ribbon domain and C-terminal MutT domain, yjad ortholog cac0145 SWALL:Q97MP7 (EMBL:AE007526) (174 aa) fasta scores: E(): 4.7e-34,54.37 38d in 160 aa. | 0.736 |
| pnpA | nnrE | CBO2413 | CBO3399 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.478 |
| pnpA | rbfA | CBO2413 | CBO2417A | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.697 |
| pnpA | rhlE | CBO2413 | CBO0643 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Putative ATP-dependent RNA helicase rhle; Belongs to the DEAD box helicase family. | 0.923 |
| pnpA | rho | CBO2413 | CBO0134 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.947 |
| pnpA | rplC | CBO2413 | CBO3480 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.874 |
| pnpA | rplD | CBO2413 | CBO3479 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.901 |
| pnpA | rplJ | CBO2413 | CBO3490 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | 0.814 |