Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0672Conserved hypothetical protein. (227 aa)    
Predicted Functional Partners:
CBO1751
Bacteriophage endolysin (N-acetylmuramoyl-L-alanine amidase); Also similar to CBO1653 (81.6 38d), CBO2325 (86.1 id.), CBO3016 (50.0 38d.).
  
     0.475
CBO1442
Putative secreted protease (pseudogene); Extracellular zinc metalloprotease.
  
     0.460
CBO1443
Putative secreted protease; Extracellular zinc metalloprotease.
  
     0.457
CBO1424
Putative N-acetylmuramoyl-L-alanine amidase; Also similar to prophage encoded CBO1751, CBO1653,CBO3016 and CBO2325.
  
     0.455
CBO1445
Putative secreted protease; Also similar to CBO1440 (pseudogene), CBO1442,CBO1443, CBO1444, CBO1446.
  
     0.454
CBO1446
Putative secreted protease; Extracellular zinc metalloprotease.
  
     0.444
CBO1444
Putative secreted protease; Extracellular zinc metalloprotease.
  
     0.437
CBO2325
Putative N-acetylmuramoyl-L-alanine amidase; Similar to the N-terminal region of Anabaena sp. hypothetical protein ALL1140 SWALL:Q8YXS1 (EMBL:AP003584) (313 aa) fasta scores: E(): 5.2e-30, 45.1 38d in 235 aa; Also similar to CBO1751 (81.16 38d), CBO1653 (77.4 id.), CBO3016 (47.6 38d.).
  
     0.429
CBO0243
Putative peroxidase; Similar to Ascophyllum nodosum vanadium haloperoxidase SWALL:PRXV_ASCNO (SWALL:P81701) (557 aa) fasta scores: E(): 5.9e-25, 34.79 38d in 523 aa, and to Laminaria digitata vanadium-dependent bromoperoxidase 2 VbpO2 SWALL:CAD37192 (EMBL:AJ491787) (682 aa) fasta scores: E(): 6.3e-37, 36.1 38d in 518 aa.
  
     0.419
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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