Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0674RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)    
Predicted Functional Partners:
CBO0673
Conserved hypothetical protein.
       0.821
CBO1626
Putative membrane protein.
 
     0.718
CBO0043A
Similar to Clostridium tetani conserved protein ctc01787 SWALL:Q893M8 (EMBL:AE015942) (477 aa) fasta scores: E(): 5.7e-98, 58.62 38d in 481 aa, and to Bacillus anthracis conserved domain protein ba1754 SWALL:Q81SB1 (EMBL:AE017029) (366 aa) fasta scores: E(): 9.9e-18, 27.1 id in 380 aa.
 
     0.700
CBO3437
Putative lipoprotein; No significant database matches.
  
 
 0.540
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.534
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.518
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.491
CBO0675
Putative dihydrouridine synthase (tRNA modification protein); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
    0.485
cheR
Chemotaxis protein methyltransferase.
    
 
 0.447
CBO0781
Conserved hypothetical protein.
  
    0.430
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.