Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hsdRType I restriction enzyme R subunit. (1115 aa)    
Predicted Functional Partners:
hsdM
Type I restriction enzyme M subunit.
 
 
 0.988
hsdS
Type I restriction enzyme S subunit.
 
 
 0.986
CBO3090
Putative DNA modification methyltransferase.
 
 
 0.783
CBO1266
Putative DNA methyltransferase.
 
 
 0.749
pcrA
ATP-dependent DNA helicase.
       0.624
CBO0681
Conserved hypothetical protein; Similar to the C-terminal region of Clostridium tetani conserved hypothetical protein ctp44 SWALL:Q899X1 (EMBL:AF528097) (306 aa) fasta scores: E(): 0.00017,37.37 38d in 99 aa.
       0.492
CBO0101
Conserved hypothetical protein; Similar to Clostridium tetani DNA helicase ctc00264 SWALL:Q899C1 (EMBL:AE015936) (1352 aa) fasta scores: E(): 1e-180, 40.17 38d in 1359 aa, and to Clostridium acetobutylicum superfamily i DNA helicase cac3036 SWALL:Q97ES1 (EMBL:AE007800) (1351 aa) fasta scores: E(): 2.2e-177, 41.54 38d in 1343 aa.
 
    0.427
CBO1871
DNA integration/recombination protein.
 
   
 0.401
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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