Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsCArsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (138 aa)    
Predicted Functional Partners:
arsB
Putative arsenical pump membrane protein.
 
  
 0.957
arsR
Arsenical resistance operon repressor.
 
  
 0.907
arsA
Arsenical pump-driving ATPase.
    
 0.904
CBO0617
Putative arsenical resistance operon repressor; The C-terminal region of this CDS is similar to arsenical resistance genes such as Staphylococcus aureus arsenical resistance operon repressor ArsR SWALL:ARSR_STAAU (SWALL:P30338) (104 aa) fasta scores: E(): 0.0047, 38.27 38d in 81 aa, and its N-terminal region is similar to several including Plasmodium yoelii yoelii putative bir1 protein py02660 SWALL:EAA22137 (EMBL:AABL01000733) (346 aa) fasta scores: E(): 1.2,23.21 38d in 224 aa, and Bacillus subtilis RNA polymerase sigma-G factor SigG or SpoIIIG or bsu15330 SWALL:RPSG_BACSU (SWALL:P19 [...]
 
  
 0.833
trxA
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.774
trxC
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.774
arsD
Arsenical resistance operon trans-acting repressor.
     
 0.565
CBO0183
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family.
  
 
 0.537
engB
Probable GTP-binding protein Engb; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
    0.494
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
      
 0.489
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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