Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
CBO0759Conserved hypothetical protein (pseudogene); Pseudogene. This CDS contains an in-frame TGA stop codon. Similar to Halobacterium sp. orf h1434 vng5177C SWALL:O52025 (EMBL:AF016485) (391 aa) fasta scores: E(): 3.1e-38, 44.44 38d in 279 aa. (182 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase; This CDS is also similar to CBO1992 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.652
pfkB
Probable sugar kinase; This CDS is also similar to CBO1763 (35.644 identity in 303 aa overlap); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.652
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.597
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.580
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.495
pgcA
Alpha-phosphoglucomutase.
  
  
 0.467
CBO3619
Putative phosphoglucomutase/phosphomannomutase.
  
  
 0.467
hemD
Porphyrin biosynthesis protein [includes: uroporphyrin-III C-methyltransferase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family.
     
 0.466
CBO0210
NAD-dependent malic enzyme; Similar to Bacillus stearothermophilus NAD-dependent malic enzyme SWALL:MAOX_BACST (SWALL:P16468) (478 aa) fasta scores: E(): 7e-79, 59.38 38d in 389 aa,and to Clostridium tetani NAD-dependent malic enzyme ctc00356 SWALL:Q898T6 (EMBL:AE015937) (389 aa) fasta scores: E(): 6.1e-102, 73.52 38d in 389 aa; Also similar to CBO0246 (66.6 38d).
      
 0.463
CBO0246
Similar to Corynebacterium melassecola malic enzyme MalE SWALL:Q9KIF8 (EMBL:AF234535) (392 aa) fasta scores: E(): 3.3e-63, 52.91 38d in 378 aa, and to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 2.7e-57, 48.88 id in 403 aa; Also similar to CBO0210 (66.6 38d).
      
 0.463
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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