Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobCAlpha-ribazole-5'-phosphate phosphatase; Belongs to the phosphoglycerate mutase family. (204 aa)    
Predicted Functional Partners:
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
 
 0.998
cbiH
Precorrin-3b C17-methyltransferase.
 
  
 0.948
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.881
cbiL
Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
  
  
 0.707
cbiT
Precorrin-8w decarboxylase.
 
  
 0.705
cobU
Bifunctional cobalamin biosynthesis protein [includes: cobinamide kinase; cobinamide phosphate guanylyltransferase].
 
  
 0.686
cobH
Precorrin-8x methylmutase.
 
  
 0.677
pgK
Phosphoglycerate kinase; Similar to Bacillus megaterium phosphoglycerate kinase Pgk SWALL:PGK_BACME (SWALL:P24269) (394 aa) fasta scores: E(): 2.4e-80, 57.07 38d in 396 aa, and to Clostridium acetobutylicum phosphoglycerate kinase Pgk or cac0710 SWALL:PGK_CLOAB (SWALL:O52632) (397 aa) fasta scores: E(): 5.4e-110, 77.44 38d in 399 aa.
    
 0.674
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
   
 0.647
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.621
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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