Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0855MerR-family transcriptional regulator. (275 aa)    
Predicted Functional Partners:
CBO0856
Putative acetyltransferase.
 
     0.877
CBO1781
Putative exported protein; No significant database matches.
  
   0.661
CBO0778
Putative membrane protein.
  
     0.640
CBO1013
Putative cyclase.
  
     0.614
CBO1954
MerR-family transcriptional regulator.
  
     0.602
CBO2781
AraC-family transcriptional regulator.
 
  
 0.584
CBO0413
Putative lipoprotein; Similar to Clostridium tetani conserved protein ctc00544 SWALL:Q898B9 (EMBL:AE015937) (381 aa) fasta scores: E(): 8.2e-56, 44.75 38d in 362 aa.
  
     0.557
CBO2268
Conserved hypothetical protein.
  
    0.547
CBO0857
Hypothetical protein; No significant database matches.
       0.540
CBO0750
Putative transposase (partial); Partial CDS. Similar to internal regions of several transposases including Thiobacillus ferrooxidans resolvase-like protein SWALL:O33828 (EMBL:U73041) (859 aa) fasta scores: E(): 4.3e-18, 42.74 38d in 124 aa, and to Streptomyces fradiae transposase for transposon tn4556 tnpA SWALL:TNPA_STRFR (SWALL:P20189) (892 aa) fasta scores: E(): 6.4, 26.44 38d in 121 aa; was marked partial.
  
    0.521
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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