STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0873Conserved hypothetical protein. (310 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.752
sigA
RNA polymerase sigma factor (sigma-43); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.742
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.736
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.735
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.680
CBO0872
Conserved hypothetical protein.
       0.550
CBO1995
Conserved hypothetical protein.
  
     0.496
CBO0328
Conserved hypothetical protein; Similar to the C-terminal region of Clostridium acetobutylicum uncharacterized conserved protein cac3492 SWALL:Q97DI5 (EMBL:AE007846) (290 aa) fasta scores: E(): 3.4e-15, 41.04 38d in 134 aa.
 
     0.479
CBO1550
LuxR-family tanscriptional regulator (partial); PS00622 Bacterial regulatory proteins, luxR family signature.
 
     0.472
CBO0327
Radical SAM superfamily protein; Similar to Clostridium acetobutylicum uncharacterized conserved protein cac3492 SWALL:Q97DI5 (EMBL:AE007846) (290 aa) fasta scores: E(): 2.2e-20,54.63 38d in 108 aa.
 
     0.424
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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