Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cotASpore coat protein. (599 aa)    
Predicted Functional Partners:
CBO1039
Putative heavy metal transporter.
  
 
 0.569
CBO1505
Putative oxidoreductase.
  
  
 0.566
CBO2485
Transposase (partial); Probable gene remnant. Similar to the C-terminal region of Streptococcus pyogenes transposase SWALL:Q9FB00 (EMBL:AB030747) (428 aa) fasta scores: E(): 9.1e-05,52.17 38d in 46 aa; was marked partial.
  
  
 0.532
CBO2486
Putative membrane protein.
  
  
 0.532
CBO3256
Putative permease.
  
  
 0.532
CBO0891
Conserved hypothetical protein.
       0.516
CBO2765
Conserved hypothetical protein.
 
 0.476
CBO0336
Similar to Clostridium acetobutylicum sensory transduction histidine kinase cac0903 SWALL:Q97KL4 (EMBL:AE007605) (683 aa) fasta scores: E(): 3e-47, 32.62 id in 610 aa.
  
 
 0.423
CBO0273
Similar to Clostridium tetani two-component sensor histidine kinase ctc00393 SWALL:Q898Q0 (EMBL:AE015937) (352 aa) fasta scores: E(): 9.2e-107, 85.22 38d in 352 aa.
 
 
 0.419
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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