Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0906Two component sensor kinase. (343 aa)    
Predicted Functional Partners:
CBO0905
Two component response regulator.
 
 
 0.970
CBO0506
Putative two-component response regulator.
 
 
 0.885
CBO3349A
Two-component response regulator.
 
 
 0.821
CBO2285
Two-component response regulator.
 
 
 0.813
CBO0365
Two-component response regulator; Similar to Enterococcus faecium regulatory protein VanR vanR SWALL:VANR_ENTFC (SWALL:Q06239) (231 aa) fasta scores: E(): 2.2e-41, 51.94 38d in 231 aa.
 
 
 0.809
CBO1613
Two-component response regulator.
 
 
 0.803
CBO0610
Two-component response regulator.
 
 
 0.801
CBO2527
Two-component response regulator.
 
 0.801
CBO1968
Two-component response regulator.
 
 
 0.797
CBO1041
Two-component response regulator.
 
 
 0.796
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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