| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiF | cbiL | CBO0947 | CBO0946 | Precorrin-4 C11-methyltransferase. | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.983 |
| cbiF | cobB | CBO0947 | CBO0924 | Precorrin-4 C11-methyltransferase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.933 |
| cbiF | hemB | CBO0947 | CBO0923 | Precorrin-4 C11-methyltransferase. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.642 |
| cbiF | hemC | CBO0947 | CBO0920 | Precorrin-4 C11-methyltransferase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.677 |
| cbiF | hemD | CBO0947 | CBO0921 | Precorrin-4 C11-methyltransferase. | Porphyrin biosynthesis protein [includes: uroporphyrin-III C-methyltransferase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | 0.773 |
| cbiL | cbiF | CBO0946 | CBO0947 | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Precorrin-4 C11-methyltransferase. | 0.983 |
| cbiL | cobB | CBO0946 | CBO0924 | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.898 |
| cbiL | hemB | CBO0946 | CBO0923 | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.643 |
| cbiL | hemC | CBO0946 | CBO0920 | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.659 |
| cbiL | hemD | CBO0946 | CBO0921 | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Porphyrin biosynthesis protein [includes: uroporphyrin-III C-methyltransferase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | 0.976 |
| cbiL | ribD | CBO0946 | CBO2866 | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.450 |
| cobB | cbiF | CBO0924 | CBO0947 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C11-methyltransferase. | 0.933 |
| cobB | cbiL | CBO0924 | CBO0946 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.898 |
| cobB | hemB | CBO0924 | CBO0923 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.692 |
| cobB | hemC | CBO0924 | CBO0920 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.515 |
| cobB | hemD | CBO0924 | CBO0921 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Porphyrin biosynthesis protein [includes: uroporphyrin-III C-methyltransferase and uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family. | 0.795 |
| hemB | cbiF | CBO0923 | CBO0947 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Precorrin-4 C11-methyltransferase. | 0.642 |
| hemB | cbiL | CBO0923 | CBO0946 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Precorrin-2 C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway. | 0.643 |
| hemB | cobB | CBO0923 | CBO0924 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.692 |
| hemB | hemC | CBO0923 | CBO0920 | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.999 |