Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0970Two-component response regulator. (240 aa)    
Predicted Functional Partners:
CBO0971
Two-component sensor kinase.
 
 
 0.966
CBO0336
Similar to Clostridium acetobutylicum sensory transduction histidine kinase cac0903 SWALL:Q97KL4 (EMBL:AE007605) (683 aa) fasta scores: E(): 3e-47, 32.62 id in 610 aa.
 
 
 0.848
CBO0340
Two-component sensor kinase; Similar to Clostridium acetobutylicum sensory transduction histidine kinase cac0903 SWALL:Q97KL4 (EMBL:AE007605) (683 aa) fasta scores: E(): 1.1e-45,34.81 38d in 586 aa.
 
 
 0.804
CBO3349
Two-component sensor kinase.
 
 
 0.799
CBO0608
Two-component sensor kinase.
 
   0.786
CBO0611
Two-component sensor kinase.
 
 
 0.781
CBO1925
Two-component sensor kinase.
 
 
 0.773
CBO2284
Two-component sensor kinase.
 
   0.770
cssS
Two-component sensor kinase; Similar to Bacillus subtilis sensor protein CssS or bsu33020 SWALL:CSSS_BACSU (SWALL:O32193) (451 aa) fasta scores: E(): 9e-33, 30.17 38d in 464 aa.
 
   0.769
CBO0906
Two component sensor kinase.
 
 
 0.759
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (26%) [HD]