Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glcALactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (507 aa)    
Predicted Functional Partners:
CBO1006
Conserved hypothetical protein.
 
   
 0.948
glcD
Glycolate oxidase subunit.
 
  
 0.920
CBO3119
Putative FMN-dependent dehydrogenase.
 
  
 0.756
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
 
  
 0.754
CBO0038
Conserved hypothetical protein; Similar to Clostridium acetobutylicum predicted enzyme with TIM-barrel fold cac0148 SWALL:Q97MP4 (EMBL:AE007526) (228 aa) fasta scores: E(): 1.9e-61,73.79 38d in 229 aa, and to Thermoanaerobacter tengcongensis hypothetical protein Tte2521 SWALL:Q8R798 (EMBL:AE013193) (227 aa) fasta scores: E(): 7.2e-52, 69.3 id in 215 aa.
  
  
 0.673
etfB
Electron transfer flavoprotein beta-subunit.
     
 0.668
etfB-2
Electron transfer flavoprotein alpha-subunit.
 
   
 0.614
nifJ2
Pyruvate-flavodoxin oxidoreductase; Also similar to CBO1192 (65.74 38d).
     
 0.606
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
     
 0.558
ackA
Conserved hypothetical protein (pseudogene); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.553
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (22%) [HD]