Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cypCFatty acid beta-hydroxylating cytochrome P450. (419 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
    
 0.940
CBO2587
Putative AMP-binding enzyme; Similar to an internal region of Bacillus licheniformis bacitracin synthetase 1 BacA SWALL:BACA_BACLI (SWALL:O68006) (5255 aa) fasta scores: E(): 4.3e-49, 33.15 38d in 561 aa.
  
 0.908
CBO2068
Putative glucosyltransferase.
  
 
 0.814
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.739
CBO2293
Short chain dehydrogenase; C-terminal region is similar to Bacillus megaterium glucose 1-dehydrogenase III GdhIII SWALL:DHG3_BACME (SWALL:P39484) (261 aa) fasta scores: E(): 2.9e-23, 34.41 id in 247 aa. Full length CDS is similar to Clostridium acetobutylicum predicted dehydrogenase of short-chain alcohol dehydrogenase family, ortholog of YhdF B.subtilis CAC1423 SWALL:Q97J63 (EMBL:AE007653) (299 aa) fasta scores: E(): 1.8e-76, 68.7 38d in 294 aa.
  
 
 0.593
CBO1664
Short-chain dehydrogenase.
  
 
 0.590
CBO2584
Putative chain-fatty-acid-CoA ligase.
  
 0.586
fldL
Putative CoA-ligase.
  
 0.586
CBO1525
Conserved hypothetical protein.
  
     0.543
CBO1505
Putative oxidoreductase.
 
 0.538
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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