| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBO1079 | cobD | CBO1079 | CBO0916 | Putative phosphoserine phosphatase. | L-threonine-O-3-phosphate decarboxylase. | 0.568 |
| CBO1079 | hisA | CBO1079 | CBO1570 | Putative phosphoserine phosphatase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.640 |
| CBO1079 | hisB | CBO1079 | CBO1568 | Putative phosphoserine phosphatase. | Imidazoleglycerol-phosphate dehydratase; Similar to the C-terminal region of the Escherichia coli entry which corresponds to the imidazoleglycerol-phosphate dehydratase domain. | 0.669 |
| CBO1079 | hisC | CBO1079 | CBO1571 | Putative phosphoserine phosphatase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.568 |
| CBO1079 | hisD | CBO1079 | CBO1567 | Putative phosphoserine phosphatase. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.654 |
| CBO1079 | hisE | CBO1079 | CBO1574 | Putative phosphoserine phosphatase. | phosphoribosyl-ATP pyrophosphatase; Similar to the C-terminal region of histidine biosynthesis bifunctional protein HisIE which corresponds to the phosphoribosyl-ATP pyrophosphohydrolase domain. | 0.609 |
| CBO1079 | hisF | CBO1079 | CBO1572 | Putative phosphoserine phosphatase. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.678 |
| CBO1079 | hisH | CBO1079 | CBO1569 | Putative phosphoserine phosphatase. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.661 |
| CBO1079 | hisI | CBO1079 | CBO1573 | Putative phosphoserine phosphatase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.666 |
| CBO1079 | hisZ | CBO1079 | CBO1565 | Putative phosphoserine phosphatase. | Putative ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.621 |
| cobD | CBO1079 | CBO0916 | CBO1079 | L-threonine-O-3-phosphate decarboxylase. | Putative phosphoserine phosphatase. | 0.568 |
| cobD | hisA | CBO0916 | CBO1570 | L-threonine-O-3-phosphate decarboxylase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.849 |
| cobD | hisB | CBO0916 | CBO1568 | L-threonine-O-3-phosphate decarboxylase. | Imidazoleglycerol-phosphate dehydratase; Similar to the C-terminal region of the Escherichia coli entry which corresponds to the imidazoleglycerol-phosphate dehydratase domain. | 0.909 |
| cobD | hisD | CBO0916 | CBO1567 | L-threonine-O-3-phosphate decarboxylase. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.905 |
| cobD | hisE | CBO0916 | CBO1574 | L-threonine-O-3-phosphate decarboxylase. | phosphoribosyl-ATP pyrophosphatase; Similar to the C-terminal region of histidine biosynthesis bifunctional protein HisIE which corresponds to the phosphoribosyl-ATP pyrophosphohydrolase domain. | 0.811 |
| cobD | hisF | CBO0916 | CBO1572 | L-threonine-O-3-phosphate decarboxylase. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.875 |
| cobD | hisH | CBO0916 | CBO1569 | L-threonine-O-3-phosphate decarboxylase. | Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.870 |
| cobD | hisI | CBO0916 | CBO1573 | L-threonine-O-3-phosphate decarboxylase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.858 |
| cobD | hisZ | CBO0916 | CBO1565 | L-threonine-O-3-phosphate decarboxylase. | Putative ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.778 |
| hisA | CBO1079 | CBO1570 | CBO1079 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | Putative phosphoserine phosphatase. | 0.640 |