Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
metN1Putative D-methionine ABC transporter,ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (318 aa)    
Predicted Functional Partners:
metI1
Putative D-methionine ABC transporter, permease protein.
 
 0.999
metI2
D-methionine ABC transporter, permease protein.
 
 0.995
metQ1
D-methionine-binding lipoprotein; Belongs to the nlpA lipoprotein family.
 
 0.994
metQ2
D-methionine-binding lipoprotein; Belongs to the nlpA lipoprotein family.
 
 0.991
metQ3
D-methionine ABC transporter, substrate-binding lipoprotein.
 
 0.986
metN2
D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
  
  
 
0.903
metF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.644
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.631
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
    0.613
CBO0087
Similar to Clostridium tetani ABC transporter permease protein ctc00486 SWALL:Q898G6 (EMBL:AE015937) (404 aa) fasta scores: E(): 1e-60, 47.66 38d in 407 aa,and to Thermoanaerobacter tengcongensis ABC-type transport systems, involved in lipoprotein release, permease components tte1198 SWALL:Q8RAL5 (EMBL:AE013082) (405 aa) fasta scores: E(): 4.1e-65, 50.73 38d in 406 aa.
 
      0.566
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.