Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
gapA2Glyceraldehyde 3-phosphate dehydrogenase A; Also similar to CBO0226 (66.26 38d); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)    
Predicted Functional Partners:
pgK
Phosphoglycerate kinase; Similar to Bacillus megaterium phosphoglycerate kinase Pgk SWALL:PGK_BACME (SWALL:P24269) (394 aa) fasta scores: E(): 2.4e-80, 57.07 38d in 396 aa, and to Clostridium acetobutylicum phosphoglycerate kinase Pgk or cac0710 SWALL:PGK_CLOAB (SWALL:O52632) (397 aa) fasta scores: E(): 5.4e-110, 77.44 38d in 399 aa.
 
 0.997
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 0.997
fba
Similar to Entamoeba histolytica putative fructose-1,6-bisphosphate aldolase Ald SWALL:Q8MTW2 (EMBL:AY057996) (326 aa) fasta scores: E(): 5.8e-51, 49.2 id in 315 aa, and to Clostridium tetani fructose-bisphosphate aldolase ctc00341 SWALL:Q898U8 (EMBL:AE015937) (320 aa) fasta scores: E(): 3.3e-80,76.75 38d in 314 aa.
  
 0.971
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.968
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.952
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.931
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.927
tkt
Transketolase, pyridine binding subunit; Similar to C-terminal region of several transketolases including Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 6e-37, 40.69 38d in 317 aa.
    
  0.906
tkt-2
Transketolase, thiamine disphosphate-bindin subunit; Similar to the N-terminal region of several transketolase including Homo sapiens transketolase Tkt or Tkt1 SWALL:TKT_HUMAN (SWALL:P29401) (623 aa) fasta scores: E(): 3.8e-36, 42.85 38d in 273 aa.
    
 0.906
gap1
Similar to Bacillus megaterium glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACME (SWALL:P23722) (334 aa) fasta scores: E(): 4.3e-78, 64.86 id in 333 aa, and to Bacillus stearothermophilus glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACST (SWALL:P00362) (334 aa) fasta scores: E(): 4.1e-82, 69.06 38d in 333 aa; Also similar to CBO1095 (66.26 38d).
  
  
 
0.901
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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