Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aldHAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (456 aa)    
Predicted Functional Partners:
adhE
Similar to Clostridium acetobutylicum aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Aad or cap0162 SWALL:ADHE_CLOAB (SWALL:P33744) (862 aa) fasta scores: E(): 2.6e-212,65.04 38d in 861 aa, and to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Ana or b1241 or z20 [...]
  
 0.963
ackA
Conserved hypothetical protein (pseudogene); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.957
gadA
Glutamate decarboxylase alpha; Belongs to the group II decarboxylase family.
  
 0.924
CBO1197
Putative flavin containing amine oxidoreductase.
   
 0.911
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.906
CBO2235
Putative glycerate kinase; Belongs to the glycerate kinase type-1 family.
   
 
 0.905
CBO0629
N-carbamoyl-L-amino acid hydrolase.
    
 0.903
eutE
Putative aldehyde-alcohol dehydrogenase.
     
 0.903
CBO1023
Putative hydrolase.
  
 
  0.902
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.901
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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