mgtE protein (Clostridium botulinum A ATCC 3502)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

mgtE

Putative Mg2+ transporter; Acts as a magnesium transporter. (452 aa)

Predicted Functional Partners:

leuS

0.694

CBO0093

0.555

CBO1123

0.509

flhA

0.505

mgtA

0.454

gcvP-2

0.451

mntP

0.447

mntP-2

0.447

guaA

0.440

Your Current Organism:

Clostridium botulinum A ATCC 3502

NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBO0093	gcvP-2	CBO0093	CBO0699	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.568
CBO0093	guaA	CBO0093	CBO3295	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.406
CBO0093	mgtA	CBO0093	CBO2869	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	Mg(2+) transport atpase, P-type 1.	0.833
CBO0093	mgtE	CBO0093	CBO1124	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	Putative Mg2+ transporter; Acts as a magnesium transporter.	0.555
CBO0093	mntP	CBO0093	CBO0394	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.	0.594
CBO0093	mntP-2	CBO0093	CBO1290	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.	0.594
CBO1123	mgtE	CBO1123	CBO1124	Hypothetical protein; No significant database matches.	Putative Mg2+ transporter; Acts as a magnesium transporter.	0.509
flhA	mgtE	CBO2645	CBO1124	Putative flagellar biosynthesis protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.	Putative Mg2+ transporter; Acts as a magnesium transporter.	0.505
gcvP-2	CBO0093	CBO0699	CBO0093	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	0.568
gcvP-2	guaA	CBO0699	CBO3295	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.458
gcvP-2	mgtA	CBO0699	CBO2869	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Mg(2+) transport atpase, P-type 1.	0.439
gcvP-2	mgtE	CBO0699	CBO1124	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Putative Mg2+ transporter; Acts as a magnesium transporter.	0.451
gcvP-2	mntP	CBO0699	CBO0394	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.	0.570
gcvP-2	mntP-2	CBO0699	CBO1290	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Putative membrane protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.	0.570
guaA	CBO0093	CBO3295	CBO0093	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Putative cations transporter; Similar to Bacillus subtilis SapB protein or bsu06650 SWALL:SAPB_BACSU (SWALL:Q45514) (232 aa) fasta scores: E(): 7.7e-13, 28.15 38d in 206 aa, and to Clostridium perfringens probable Mg2+ transport protein cpe0592 SWALL:Q8XMU6 (EMBL:AP003187) (241 aa) fasta scores: E(): 1.2e-27, 39.24 38d in 237 aa.	0.406
guaA	gcvP-2	CBO3295	CBO0699	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.458
guaA	leuS	CBO3295	CBO0186	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Similar to Escherichia coli leucyl-tRNA synthetase LeuS or b0642 SWALL:SYL_ECOLI (SWALL:P07813) (860 aa) fasta scores: E(): 4.7e-104, 40.67 38d in 858 aa, and to Clostridium tetani leucyl-tRNA synthetase LeuSor ctc00337 SWALL:SYL_CLOTE (SWALL:Q898V2) (812 aa) fasta scores: E(): 0, 76.26 38d in 813 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.651
guaA	mgtE	CBO3295	CBO1124	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Putative Mg2+ transporter; Acts as a magnesium transporter.	0.440
leuS	guaA	CBO0186	CBO3295	Similar to Escherichia coli leucyl-tRNA synthetase LeuS or b0642 SWALL:SYL_ECOLI (SWALL:P07813) (860 aa) fasta scores: E(): 4.7e-104, 40.67 38d in 858 aa, and to Clostridium tetani leucyl-tRNA synthetase LeuSor ctc00337 SWALL:SYL_CLOTE (SWALL:Q898V2) (812 aa) fasta scores: E(): 0, 76.26 38d in 813 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.651
leuS	mgtE	CBO0186	CBO1124	Similar to Escherichia coli leucyl-tRNA synthetase LeuS or b0642 SWALL:SYL_ECOLI (SWALL:P07813) (860 aa) fasta scores: E(): 4.7e-104, 40.67 38d in 858 aa, and to Clostridium tetani leucyl-tRNA synthetase LeuSor ctc00337 SWALL:SYL_CLOTE (SWALL:Q898V2) (812 aa) fasta scores: E(): 0, 76.26 38d in 813 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.	Putative Mg2+ transporter; Acts as a magnesium transporter.	0.694