Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysK2Cysteine synthase 2; Also similar to CBO0205 (53.5 38d); Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)    
Predicted Functional Partners:
cysE
Similar to Bacillus subtilis serine acetyltransferase CysE or CusA or bsu00930 SWALL:CYSE_BACSU (SWALL:Q06750) (217 aa) fasta scores: E(): 4.3e-35, 61.07 38d in 167 aa, and to Clostridium tetani serine acetyltransferase ctc00351 SWALL:Q898U0 (EMBL:AE015937) (186 aa) fasta scores: E(): 2.6e-47,74.45 38d in 184 aa.
 
 0.996
metC
Cystathionine beta-lyase.
  
 0.965
mdeA
Similar to Pseudomonas putida methionine gamma-lyase MdeA SWALL:MEGL_PSEPU (SWALL:P13254) (398 aa) fasta scores: E(): 3e-82, 53.03 38d in 396 aa, and to Clostridium tetani cys/met metabolism lyase ctc02530 SWALL:Q890V5 (EMBL:AE015944) (398 aa) fasta scores: E(): 3.2e-115, 73.61 38d in 398 aa.
  
 0.931
CBO1400
Putative aminotransferase.
    
 0.914
CBO1963
Putative aminotransferase.
    
 0.914
cysK
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 
0.905
asrB
Anaerobic sulfite reductase subunit B.
   
 
 0.905
asrC
Anaerobic sulfite reductase subunit c.
  
 
  0.904
cysK1
Cysteine synthase 1; Also similar to CBO0205 (53.5 38d); Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 
0.903
CBO1014
Putative aromatic amino acid aminotransferase.
   
 
 0.902
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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