STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO1197Putative flavin containing amine oxidoreductase. (577 aa)    
Predicted Functional Partners:
adhE
Similar to Clostridium acetobutylicum aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Aad or cap0162 SWALL:ADHE_CLOAB (SWALL:P33744) (862 aa) fasta scores: E(): 2.6e-212,65.04 38d in 861 aa, and to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Ana or b1241 or z20 [...]
    
 0.914
aldH
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.911
fldH
D-phenyllactate dehydrogenase; Downstream convergently transcribed paralogue; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.901
CBO1174
Putative acetyltransferase.
     
  0.900
dkgA
2,5-diketo-D-gluconic acid reductase.
   
 
 0.808
CBO1595
Putative helicase.
    
 0.697
CBO1670
Putative helicase.
    
 0.697
CBO0364
Putative phosphatase; Similar to Clostridium tetani ser/thr and tyr protein phosphatase ctc02044 SWALL:Q892P9 (EMBL:AE015943) (208 aa) fasta scores: E(): 6e-36, 43.35 38d in 203 aa.
   
  
 0.676
yabQ
Putative membrane protein.
  
     0.639
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
   
    0.595
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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