STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
grdEPutative component of glycine reductase complex. (428 aa)    
Predicted Functional Partners:
grdB
Putative glycine reductase complex component b gamma subunit; Selenoprotein. This CDS contains an opal stop codon that is read-through as selenocysteine.
 
   
 0.980
grdA
Glycine/sarcosine/betaine reductase complex component A; Selenoprotein. This CDS contains an opal stop codon that is read-through as selenocysteine.
 
   
 0.956
grdX
Putative component of glycine reductase complex.
 
   
 0.953
grdC
Glycine/sarcosine/betaine reductase complex component C beta subunit.
 
   
 0.916
grdD
Putative glycine/sarcosine/betaine reductase complex component C alpha subunit; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
   
 0.914
trxA
Thioredoxin; Belongs to the thioredoxin family.
 
   
 0.887
prdB1
Similar to Clostridium sticklandii proline reductase PrdB SWALL:Q9Z4Q7 (EMBL:AJ130879) (242 aa) fasta scores: E(): 8.5e-70, 79.07 38d in 239 aa. CDS contains an in frame UGA codon for probable selenocysteine insertion.
 
   
 0.690
prdB2
Putative subunit of proline reductase; Similar to Clostridium sticklandii proline reductase PrdB SWALL:Q9Z4Q7 (EMBL:AJ130879) (242 aa) fasta scores: E(): 1.1e-71, 80.33 38d in 239 aa. CDS contains an in frame UGA codon for probable selenocysteine insertion.
 
   
 0.655
trxB2
Thioredoxin reductase.
 
    0.631
prdD
Putative component of proline reductase.
 
   
 0.562
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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