Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
grdDPutative glycine/sarcosine/betaine reductase complex component C alpha subunit; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (388 aa)    
Predicted Functional Partners:
grdC
Glycine/sarcosine/betaine reductase complex component C beta subunit.
  
 0.997
grdA
Glycine/sarcosine/betaine reductase complex component A; Selenoprotein. This CDS contains an opal stop codon that is read-through as selenocysteine.
 
   
 0.941
grdE
Putative component of glycine reductase complex.
 
   
 0.914
grdB
Putative glycine reductase complex component b gamma subunit; Selenoprotein. This CDS contains an opal stop codon that is read-through as selenocysteine.
 
   
 0.909
grdX
Putative component of glycine reductase complex.
 
   
 0.905
trxA
Thioredoxin; Belongs to the thioredoxin family.
 
     0.819
fabD
Malonyl CoA-acyl carrier protein transacylase.
  
  
 0.773
rpmF
50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.750
rpsM
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
    0.730
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
    0.720
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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