Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO1316Putative type IV prepilin signal peptidase. (255 aa)    
Predicted Functional Partners:
CBO1908
General secretion pathway protein.
 
  
 0.946
CBO1909
General secretion pathway protein.
 
 
 0.923
CBO2539
Putative twitching mobility protein.
 
   
 0.860
dprA
SMF family protein; C-terminus is similar to the C-terminal region of Haemophilus influenzae Smf protein HI0985 SWALL:SMF_HAEIN (SWALL:P43862) (373 aa) fasta scores: E(): 3e-26, 35.64 id in 317 aa, and to Clostridium tetani Smf protein,putative DNA processing chain A CTC01258 SWALL:Q895L5 (EMBL:AE015940) (361 aa) fasta scores: E(): 1.5e-65,54.69 38d in 362 aa.
 
  
 0.793
CBO1907
Putative pilin.
 
  
 0.757
CBO2978
Putative competence protein.
   
  
 0.741
CBO0170
Similar to Clostridium tetani conserved protein ctc00323 SWALL:Q898W5 (EMBL:AE015937) (354 aa) fasta scores: E(): 9.6e-44, 38.26 38d in 345 aa.
   
  
 0.666
CBO1001
Putative membrane protein (competence protein).
   
  
 0.648
CBO2969
Putative competence protein.
  
  
 0.620
aroE
Putative shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.591
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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