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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO1391Putative peptide methionine sulfoxide reductase. (212 aa)    
Predicted Functional Partners:
msrB
Putative methionine sulfoxide reductase; Similar to the C-terminal region of Streptococcus pneumoniae, and Streptococcus pneumoniae peptide methionine sulfoxide reductase MsrA/MsrB 2 MsrAB2 or msrA or sp0660 or spr0577 SWALL:MAB2_STRPN (SWALL:Q97RX3) (311 aa) fasta scores: E(): 6.1e-34, 63.12 38d in 141 aa, and to the full length Clostridium perfringens peptide methionine sulfoxide reductase CPE1607 SWALL:MSRB_CLOPE (SWALL:Q8XJZ6) (147 aa) fasta scores: E(): 2.4e-49, 84.13 id in 145 aa.
 
 0.982
CBO2765
Conserved hypothetical protein.
   
 0.841
grxC
Putative glutaredoxin.
  
 
 0.793
ccdA2
Cytochrome C-type biogenesis protein.
   
 
 0.670
metH
Putative methionine synthase.
  
  
 0.530
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.450
CBO0183
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family.
   
 
 0.442
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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