Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO1399Conserved hypothetical protein. (334 aa)    
Predicted Functional Partners:
CBO0655
PTS system, beta-glucoside-specific IIabc component.
  
  
 0.543
bglF
PTS system, beta-glucoside-specific IIabc component.
  
  
 0.543
ptsG-2
PTS system, glucose-specific IIABC component.
  
  
 0.543
ptbA-3
Putative PTS system, glucose-specific IIABC component; C-terminal region is similar to Escherichia coli,Escherichia coli O6, and Escherichia coli O157:H7 PTS system, glucose-specific IIBC component PtsG or GlcA or Umg or b1101 or c1373 or z1740 or ecs1479 SWALL:PTGB_ECOLI (SWALL:P05053) (477 aa) fasta scores: E(): 2.6e-50, 42.25 id in 497 aa. Full length CDS is similar to Bacillus subtilis putative PTS system IIABC component YbfS or bsu02350 SWALL:YBFS_BACSU (SWALL:P39816) (631 aa) fasta scores: E(): 4e-56, 41.9 38d in 642 aa.
  
  
 0.543
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
     
 0.524
CBO1398
Conserved hypothetical protein.
 
     0.515
nifJ2
Pyruvate-flavodoxin oxidoreductase; Also similar to CBO1192 (65.74 38d).
     
 0.503
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
      
 0.436
colA
Secreted collagenase.
 
    0.423
adhE
Similar to Clostridium acetobutylicum aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Aad or cap0162 SWALL:ADHE_CLOAB (SWALL:P33744) (862 aa) fasta scores: E(): 2.6e-212,65.04 38d in 861 aa, and to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase; acetaldehyde dehydrogenase [acetylating] (EC 1.2.1.10) (acdh); pyruvate-formate-lyase deactivase (pfl deactivase)] AdhE or Ana or b1241 or z20 [...]
  
  
 0.413
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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