Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
CBO1601Putative LacI-family transcriptional regulator. (333 aa)    
Predicted Functional Partners:
ptsH
Putative phosphocarrier protein HPr.
   
 
 0.832
CBO3439
Sigma-54-dependent transcriptional activator.
   
 
 0.761
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.751
glcK
Putative glucokinase.
 
  
 0.598
CBO1271
DeoR-family transcriptional regulator.
  
  
 0.591
ribA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.575
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
   0.575
glcR
DeoR-family transcriptional regulator.
  
  
 0.560
CBO2210
DeoR family regulatory proteins.
  
  
 0.546
CBO1991
PTS system, IIbc component.
     
 0.541
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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