Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO1618Weak similarity to the listed RNA polymerase sigma factors. (176 aa)    
Predicted Functional Partners:
CBO3437
Putative lipoprotein; No significant database matches.
  
 
 0.540
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.534
CBO0170
Similar to Clostridium tetani conserved protein ctc00323 SWALL:Q898W5 (EMBL:AE015937) (354 aa) fasta scores: E(): 9.6e-44, 38.26 38d in 345 aa.
  
     0.525
rpoC
DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.518
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.491
CBO0191
Putative adenylate cyclase; Similar to Clostridium acetobutylicum adenilate cyclase, class2 cac0650 SWALL:Q97LB2 (EMBL:AE007580) (180 aa) fasta scores: E(): 8.5e-37, 64.77 38d in 176 aa, and to Clostridium perfringens hypothetical protein Cpe1352 cpe1352 SWALL:Q8XKP2 (EMBL:AP003190) (187 aa) fasta scores: E(): 6.5e-36, 62.92 38d in 178 aa.
  
     0.489
CBO1619
Conserved hypothetical protein.
  
    0.478
cheR
Chemotaxis protein methyltransferase.
    
 
 0.447
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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