STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO1831Conserved hypothetical protein; Similar to the C-terminal region of stage II sporulation protein E from various organisms including Bacillus subtilis stage II sporulation protein eE SpoIIE or spoiih or bsu00640 SWALL:SP2E_BACSU (SWALL:P37475) (827 aa) fasta scores: E(): 0.0013, 27.01 38d in 211 aa. (389 aa)    
Predicted Functional Partners:
CBO1829
Conserved hypothetical protein; Similar to the C-terminal region of several oxidoreductases such as Eubacterium acidaminophilum HymA protein.
 
    0.970
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.954
CBO1830
Putative hydrogenase; This CDS is also similar to CBO1832 (49.914 38d. in 579 aa overlap).
 
     0.953
thiH
Thiazole biosynthesis protein.
  
  
 0.943
CBO1832
Putative hydrogenase; This CDS is also similar to CBO1830 (49.914 38d. in 579 aa overlap).
 
     0.895
CBO0357
Putative signaling protein; Similar to Chromobacterium violaceum hypothetical protein cv0542 SWALL:AAQ58219 (EMBL:AE016911) (633 aa) fasta scores: E(): 2.3e-57, 35.07 38d in 536 aa.
  
  
 0.776
fliG
Flagellar motor switch protein.
  
    0.769
fliM
Flagellar motor switch protein FliM.
  
    0.768
flgB
Flagellar basal-body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.750
fliY
Flagellar motor switch protein FliY.
  
    0.641
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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