Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hupDPutative hydrogenase maturation protein. (138 aa)    
Predicted Functional Partners:
hupL
Hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.958
hupS
Hydrogenase small subunit.
 
  
 0.918
hypQ3
Conserved hypothetical protein.
 
   
 0.893
hypF
Hydrogenase maturation protein.
 
   
 0.701
hypD
Hydrogenase isoenzymes formation protein.
 
   
 0.654
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
  
  
 0.610
hypE
Hydrogenase isoenzymes formation protein.
 
   
 0.588
CBO0476
Similar to Clostridium acetobutylicum hypothetical protein Cac3540 SWALL:Q97DD8 (EMBL:AE007850) (53 aa) fasta scores: E(): 1.8e-13, 60 38d in 50 aa.
  
     0.587
hymB
Putative electron-transferring subunit of iron-only hydrogenase.
  
  
 0.516
CBO0244
Similar to Bacillus subtilis hypothetical protein yrkc or bsu26560 SWALL:YRKC_BACSU (SWALL:P54430) (186 aa) fasta scores: E(): 5.7e-41, 61.45 38d in 192 aa, and to Clostridium tetani conserved protein ctc01899 SWALL:Q893C8 (EMBL:AE015942) (193 aa) fasta scores: E(): 1.1e-40,59.09 38d in 220 aa.
  
     0.504
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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